FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, > 50 μM for FXIIa, thrombin and FXIa, respectively. FXIIa-IN-4 can be used for study of anticoagulant[1].
Molecular Formula
C11H9FN4O3
Molecular Weight
264.21
Smiles
O=C(C1=NN(C(C2=CC=C(F)C=C2)=O)C(N)=N1)OC
Target
Factor Xa; Thrombin
Concentration
10mM
Purity
98.87
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)