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G5-7 [CAS 939681-36-4]

G5-7 [CAS 939681-36-4]

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SKU:QM-0138636-01

£301.50 GBP
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  • Description

    G5-7, an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5-7 has the potential for glioma study[1].

  • CAS Number

    [939681-36-4]

  • Molecular Formula

    C22H19F2NO3

  • Molecular Weight

    383.39

  • Smiles

    O=C(N1C/C(C(/C(C1)=C\C2=CC=CC=C2F)=O)=C/C3=CC=CC=C3F)OCC

  • Target

    Apoptosis; JAK

  • Isoform

    JAK2

  • Concentration

    10mM

  • Purity

    99.55

  • Solubility

    DMSO : 83.33 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Variant Variant total Quantity Price Variant total
5 mgQM-0138636-01
5 mgQM-0138636-01
£301.50/ea
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£301.50/ea £0.00
10 mM - 1 mLQM-0138636-02
10 mM - 1 mLQM-0138636-02
£325.81/ea
£0.00
£325.81/ea £0.00
10 mgQM-0138636-03
10 mgQM-0138636-03
£426.65/ea
£0.00
£426.65/ea £0.00
25 mgQM-0138636-04
25 mgQM-0138636-04
£740.12/ea
£0.00
£740.12/ea £0.00

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G5-7 [CAS 939681-36-4]

G5-7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.