G721-0282 [CAS 946378-12-7]

Name: G721-0282 [CAS 946378-12-7]
Brand: QuantiMol
SKU: QM-0010036-01
Price: 678.15 GBP
Availability: InStock

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SKU:QM-0010036-01

£678.15 GBP

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Product Details

Description
G721-0282 is an orally active CHI3L1 inhibitor. G721-0282 can reduce the expression of inflammatory proteins and cytokines. G721-0282 inhibits the activation of the NF-κB signaling pathway. G721-0282 inhibits neuroinflammation and reduces anxious behavior. G721-0282 significantly inhibits the proliferation of osteosarcoma (OS) cells by suppressing the STAT3 signaling pathway. G721-0282 induces OS cell apoptosis by upregulating pro-apoptotic protein levels and downregulating anti-apoptotic protein levels. G721-0282 can be used for researches on neuroinflammatory conditions and cancer[1][2].
CAS Number
[946378-12-7]
Molecular Formula
C18H24N4O3S
Molecular Weight
376.47
Smiles
O=C1C2=C(C(CCCC)=CN=C2N(C)C(N1C)=O)SCC(NCC=C)=O
Target
Apoptosis; Bcl-2 Family; CDK; COX; ERK; Glycosidase; NF-κB; p38 MAPK; STAT; Survivin
Isoform
Bcl-2; CDK4; CDK6; COX-2; ERK; NF-κB; p38 MAPK; STAT3
Shipping Conditions
Room temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0010036-01	5 mgQM-0010036-01 £678.15/ea	£0.00	Quantity	£678.15/ea	£0.00

10 mgQM-0010036-02	10 mgQM-0010036-02 £1,053.59/ea	£0.00	Quantity	£1,053.59/ea	£0.00

25 mgQM-0010036-03	25 mgQM-0010036-03 £1,895.59/ea	£0.00	Quantity	£1,895.59/ea	£0.00

50 mgQM-0010036-04	50 mgQM-0010036-04 £3,000.02/ea	£0.00	Quantity	£3,000.02/ea	£0.00

100 mgQM-0010036-05	100 mgQM-0010036-05 £4,820.09/ea	£0.00	Quantity	£4,820.09/ea	£0.00

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G721-0282 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.