Gamma-glutamylcysteine (TFA) [CAS 283159-88-6]
Gamma-glutamylcysteine (TFA) [CAS 283159-88-6]
SKU:QM-0138071-01
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Product Details
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Description
Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx) . Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) . Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes[1].
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CAS Number
[283159-88-6]
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Molecular Formula
C10H15F3N2O7S
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Molecular Weight
364.3
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Smiles
SC[C@@H](C(O)=O)NC(CC[C@H](N)C(O)=O)=O.OC(C(F)(F)F)=O
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Target
Endogenous Metabolite; Interleukin Related; TNF Receptor
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Isoform
Human Endogenous Metabolite; IL-1; IL-10; IL-6; TNFRSF5/CD40
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Purity
95.2
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Gamma-glutamylcysteine (TFA) [CAS 283159-88-6]
Gamma-glutamylcysteine (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.