Ganciclovir [CAS 82410-32-0]

Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain[1][2][3].

[82410-32-0]

C9H13N5O4

255.23

O=C1NC(N)=NC2=C1N=CN2COC(CO)CO

Antibiotic; CMV; HSV; Nucleoside Antimetabolite/Analog

HSV-1; HSV-2

10mM

99.89

DMSO : 60 mg/mL (ultrasonic) |H2O : 1.67 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H360

H360