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GATA4-NKX2-5-IN-1 [CAS 544681-96-1]

GATA4-NKX2-5-IN-1 [CAS 544681-96-1]

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SKU:QM-0083337-01

£401.13 GBP
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  • Description

    GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression[1].

  • CAS Number

    [544681-96-1]

  • Molecular Formula

    C21H23N3O2

  • Molecular Weight

    349.43

  • Smiles

    CC1=C(C(NC2=CC=C(N(CC)CC)C=C2)=O)C(C3=CC=CC=C3)=NO1

  • Target

    IKZF Family

  • Concentration

    10mM

  • Purity

    99.24

  • Solubility

    DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

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Variant Variant total Quantity Price Variant total
5 mgQM-0083337-01
5 mgQM-0083337-01
£401.13/ea
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£401.13/ea £0.00
10 mM - 1 mLQM-0083337-02
10 mM - 1 mLQM-0083337-02
£436.37/ea
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10 mgQM-0083337-03
10 mgQM-0083337-03
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25 mgQM-0083337-04
25 mgQM-0083337-04
£803.30/ea
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£803.30/ea £0.00
50 mgQM-0083337-05
50 mgQM-0083337-05
£1,066.95/ea
£0.00
£1,066.95/ea £0.00
100 mgQM-0083337-06
100 mgQM-0083337-06
£1,430.24/ea
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£1,430.24/ea £0.00

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GATA4-NKX2-5-IN-1 [CAS 544681-96-1]

GATA4-NKX2-5-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.