The GCDH protein is essential for the degradation of L-lysine, L-hydroxylysine, and L-tryptophan. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA, releasing CO (2) . GCDH Protein, Human (His) is the recombinant human-derived GCDH protein, expressed by E. coli , with N-6*His labeled tag.