GCO- (GPO) 10-GCOG

GCO- (GPO) 10-GCOG is a GPO repeat-containing peptide with a single collagen triple helix structure similar to collagen. The cross-linked triple helix GCO- (GPO) 10-GCOG can form a collagen-related peptide (CRP) mimetic that tightly binds to the Yersinia adhesin YadA. YadA mediates the adhesion of the human enteric pathogen Yersinia enterocolitica to collagen and other extracellular matrix components, potentially interfering with host processes mediated by endogenous collagen-binding proteins in vivo. GCO- (GPO) 10-GCOG can be used to study YadA-associated infections[1].

C142H205N37O50S2

3294.53

O=C(N[C@@H](CS)C(N1[C@@H](CC(C1)O)C(NCC(N2[C@@H](CCC2)C(N3[C@@H](CC(C3)O)C(NCC(N4[C@@H](CCC4)C(N5[C@@H](CC(C5)O)C(NCC(N6[C@@H](CCC6)C(N7[C@@H](CC(C7)O)C(NCC(N8[C@@H](CCC8)C(N9[C@@H](CC(C9)O)C(NCC(N%10[C@@H](CCC%10)C(N%11[C@@H](CC(C%11)O)C(NCC(N%12[C@@H](CCC%12)C(N%13[C@@H](CC(C%13)O)C(NCC(N%14[C@@H](CCC%14)C(N%15[C@@H](CC(C%15)O)C(NCC(N%16[C@@H](CCC%16)C(N%17[C@@H](CC(C%17)O)C(NCC(N%18[C@@H](CCC%18)C(N%19[C@@H](CC(C%19)O)C(NCC(N%20[C@@H](CCC%20)C(N%21[C@@H](CC(C%21)O)C(NCC(N[C@@H](CS)C(N%22[C@@H](CC(C%22)O)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Bacterial

Room temperature