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SKU:QM-0151424-01
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GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.
[1133432-49-1]
C33H36N6O3S
596.74
O=C(C1=CC(CCCC2)=C2S1)NC3=CC=CC(C(N=C4NC5=CC=C([C@H]6N(C)CCN(C)C6=O)C=C5)=CN(C)C4=O)=C3C
Btk
98.05
DMSO : ≥ 32 mg/mL
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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GDC-0834 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.