GDC-2394 [CAS 2238822-07-4]

Name: GDC-2394 [CAS 2238822-07-4]
Brand: QuantiMol
SKU: QM-0149629-01
Price: 520.2 GBP
Availability: InStock

Size 5 mg 10 mg 25 mg 50 mg

SKU:QM-0149629-01

£520.20 GBP

Sale Sold out

Quote Datasheet SDS COA

Product Details

Description
GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β) . GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation[1][2].
CAS Number
[2238822-07-4]
Molecular Formula
C20H25N5O4S
Molecular Weight
431.51
Smiles
O=S(C1=C2OC[C@@H](NC)CN2N=C1)(NC(NC3=C4CCCC4=CC5=C3CCC5)=O)=O
Target
Caspase; Interleukin Related; NOD-like Receptor (NLR)
Purity
99.87
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years (Powder)
Shipping Conditions
Blue Ice

Your cart
Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0149629-01	5 mgQM-0149629-01 £520.20/ea	£0.00	Quantity	£520.20/ea	£0.00

10 mgQM-0149629-02	10 mgQM-0149629-02 £803.30/ea	£0.00	Quantity	£803.30/ea	£0.00

25 mgQM-0149629-03	25 mgQM-0149629-03 £1,556.60/ea	£0.00	Quantity	£1,556.60/ea	£0.00

50 mgQM-0149629-04	50 mgQM-0149629-04 £2,460.56/ea	£0.00	Quantity	£2,460.56/ea	£0.00

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.

GDC-2394 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.