GEA 857 [CAS 120493-42-7]

GEA 857 is a structural analog of the Serotonin uptake blocker Alaproclate (HY-164011). GEA 857 enhances responses induced by muscarinic receptor agonists by inhibiting certain calcium-dependent potassium channels on membranes, a blockade that can enhance or prolong the muscarinic cholinergic effects. GEA 857 can be used in research on neurodegenerative diseases[1].

[120493-42-7]

C15H22ClNO2

283.79

N[C@@H](C(C)C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O

Potassium Channel

Room temperature