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Gefitinib impurity 1 [CAS 675126-26-8]

Gefitinib impurity 1 [CAS 675126-26-8]

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SKU:QM-0143595-01

£51.91 GBP
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  • Description

    Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].

  • CAS Number

    [675126-26-8]

  • Molecular Formula

    C15H19N3O5

  • Molecular Weight

    321.33

  • Smiles

    N#CC1=CC(OCCCN2CCOCC2)=C(OC)C=C1[N+]([O-])=O

  • Target

    Drug Metabolite

  • Purity

    99.59

  • Solubility

    DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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500 mgQM-0143595-01
500 mgQM-0143595-01
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10 mM - 1 mLQM-0143595-02
10 mM - 1 mLQM-0143595-02
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Gefitinib impurity 1 [CAS 675126-26-8]

Gefitinib impurity 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.