Gefitinib impurity 2 [CAS 246512-44-7]
Gefitinib impurity 2 [CAS 246512-44-7]
SKU:QM-0079564-01
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Product Details
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Description
Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].
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CAS Number
[246512-44-7]
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Molecular Formula
C15H23N3O4
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Molecular Weight
309.37
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Smiles
O=C(N)C1=CC(OCCCN2CCOCC2)=C(OC)C=C1N
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Target
EGFR
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Purity
99.56
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Gefitinib impurity 2 [CAS 246512-44-7]
Gefitinib impurity 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.