Germacrone [CAS 6902-91-6]

Germacrone is a sesquiterpene compound with multiple biological activities. Germacrone inhibits the H1N1 and H3N2 influenza A virus and the influenza B virus. Germacrone blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone inhibits 5α-reductase and has anti-androgenic effect. Germacrone has neuroprotective functions and can be used for the study of traumatic brain injury (TBI) . Germacrone also has antioxidant activity[1][2][3][4][5].

[6902-91-6]

C15H22O

218.33

O=C1C/C(C)=C/CC/C(C)=C/C/C1=C(C)\C

5 alpha Reductase; Apoptosis; Influenza Virus; Keap1-Nrf2; Lactate Dehydrogenase; NF-κB

99.76

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature

H315, H319, H335

H315, H319, H335