Globomycin [CAS 67076-74-8]

Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM[1][2].

[67076-74-8]

C32H57N5O9

655.82

CC(C)C[C@@](N(C([C@@H]([C@H](OC(CNC1=O)=O)CCCCCC)C)=O)C)([H])C(N[C@@](C(N[C@H](C(N[C@@]1([H])[C@@H](O)C)=O)CO)=O)([H])[C@H](C)CC)=O

Antibiotic; Bacterial

Lipopeptide

99

10 mM in DMSO

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice