[Glp5, (Me) Phe8, Sar9] Substance P (5-11) [CAS 77128-69-9]

[Glp5, (Me) Phe8, Sar9] Substance P (5-11) (DiMe-C7) is a Substance P analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. [Glp5, (Me) Phe8, Sar9] Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. [Glp5, (Me) Phe8, Sar9] Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats[1][2][3].

[77128-69-9]

C43H61N9O9S

880.06

CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CN(C)C([C@H](CC1=CC=CC=C1)N(C)C([C@@H](NC([C@H](CCC(N)=O)NC([C@@H]2CCC(N2)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O

Neurokinin Receptor

99.61

DMSO : ≥ 100 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice