Glucocorticoid receptor/IL-6-IN-2 [CAS 1198784-83-6]

Glucocorticoid receptor/IL-6-IN-2 (Compound 36) is a selective dual inhibitor targeting the glucocorticoid receptor (GR) and IL-6 signaling pathway (IC50 values of 40 nM and 19 nM, respectively) . Glucocorticoid receptor/IL-6-IN-2 is promising for research of inflammatory diseases like rheumatoid arthritis and asthma[1].

[1198784-83-6]

C22H23ClF3N3O4S

517.95

O=C(C1=CC(Cl)=CC=C1C(C)(CC(CC2=CC3=C(N2)C=NC(S(=O)(C)=O)=C3)(C(F)(F)F)O)C)N

Glucocorticoid Receptor; Interleukin Related

IL-6

Room temperature