α-Glucosidase-IN-30 [CAS 2966859-35-6]

α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study[1].

[2966859-35-6]

C20H19N7O2

389.41

O=C(NCC1=CN(CC(NC2=CC(C)=CC=C2)=O)N=N1)C3=NC4=CC=CC=C4N3

Glycosidase

10 mM in DMSO

Room temperature