α-Glucosidase/NLRP3-IN-1

α-Glucosidase/NLRP3-IN-1 (Compound 8) is a dual inhibitor of α-glucosidase and NLRP3, exhibiting an IC50 of 6.6 μM against α-glucosidase and inhibiting NLRP3 in multiple cell lines at a concentration of 100 μM. α-Glucosidase/NLRP3-IN-1 demonstrates neuroprotective and antidiabetic properties, and can be utilized in relevant research[1].

C38H54O4

574.83

CC(O)(C1CC[C@@](C2CC[C@@]3(C2CCC4[C@]5(C/C(C(C(C)(C5CC[C@]43C)C)=O)=C/C6=CC=C(C=C6)C=O)C)C)(O1)C)C

Glycosidase; NOD-like Receptor (NLR)

NLRP3

Room temperature