GLUD1 protein is a mitochondrial glutamate dehydrogenase that converts L-glutamate into α-ketoglutarate, supporting glutamine anaplerosis and the tricarboxylic acid cycle. In addition to metabolism, GLUD1 plays a key role in insulin homeostasis, complexly regulating glucose metabolism. GLUD1 Protein, Human (His) is the recombinant human-derived GLUD1 protein, expressed by E. coli , with N-6*His labeled tag.