Gly-Gly-Gly-PEG4-methyltetrazine [CAS 2353409-82-0]

Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Gly-Gly-Gly-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

[2353409-82-0]

C23H34N8O7

534.57

CC1=NN=C(N=N1)C2=CC=C(C=C2)OCCOCCOCCOCCNC(CNC(CNC(CN)=O)=O)=O

ADC Linker

Cleavable Linker

97.89

DMSO : ≥ 100 mg/mL

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice

H315, H319, H335

H315, H319, H335