Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689)[2][3].
CAS Number
[200427-88-9]
Molecular Formula
C15H20N4O5
Molecular Weight
336.34
Smiles
NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O
Target
ADC Linker; Drug Intermediate
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)