GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity[1]. GM-CSF R alpha binds to GM-CSF and induces cell differentiation[2]. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA) [3]. GM-CSF R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 298 amino acids (L30-P327) and is produced in HEK293 cells.
Molecular Formula
12982 (Gene_ID) Q00941 (L30-P327) (Accession)
Purity
95
Storage Conditions
Stored at -20°C for 2 years
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
