GM2A Protein is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2A, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. And it is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. GM2A Protein, Human (sf9, His) is the recombinant human-derived GM2A protein, expressed by Sf9 insect cells , with C-His labeled tag.
