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SKU:QM-0145268-01
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GNE-1858 is a potent and ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor, with IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA, respectively[1].
[2680616-96-8]
C21H26F2N8
428.48
FC1(CCN(C2=NC(C3CCNC3)=CC(NC4=CC5=C(C=N4)C=NN5C(C)C)=N2)C1)F
MAP4K
99.23
DMSO : 20 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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GNE-1858 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.