GNE-2256 [CAS 2102170-43-2]

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SKU:QM-0067843

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Product Details

Description
GNE-2256 (molecule 19), a chemical probe, is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM) [1].
CAS Number
[2102170-43-2]
Molecular Formula
C24H27FN6O4
Molecular Weight
482.51
Smiles
O=C(C1=C2N(C=CC=N2)N=C1)NC3=C(N4CCOCC4)C=C5C(CN(C5=O)C[C@@H](F)C(C)(O)C)=C3
Target
IRAK
Isoform
IRAK4
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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GNE-2256 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.