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SKU:QM-0112491-01
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GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.
[2026635-66-3]
C17H10Cl2F3N5O
428.2
ClC1=C([C@H]2[C@H](C#N)C2)N3C(C=C1)=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC3=O
IGluR
NMDA Receptor
99.05
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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GNE 5729 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.