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GNF-5837 [CAS 1033769-28-6]

GNF-5837 [CAS 1033769-28-6]

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QM-0144880-01

£89.13 GBP
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Product Details

  • Description

    GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays (IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) [1].

  • CAS Number

    [1033769-28-6]

  • Molecular Formula

    C28H21F4N5O2

  • Molecular Weight

    535.49

  • Smiles

    O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2

  • Target

    Trk Receptor

  • Isoform

    TrkA; TrkB; TrkC

  • Concentration

    10mM

  • Purity

    99.44

  • Solubility

    DMSO : ≥ 32 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0144880-01
5 mgQM-0144880-01
£89.13/ea		 £0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0144880-02
10 mM - 1 mLQM-0144880-02
£100.38/ea		 £0.00
£100.38/ea £0.00
10 mgQM-0144880-03
10 mgQM-0144880-03
£139.75/ea		 £0.00
£139.75/ea £0.00
25 mgQM-0144880-04
25 mgQM-0144880-04
£256.55/ea		 £0.00
£256.55/ea £0.00
50 mgQM-0144880-05
50 mgQM-0144880-05
£381.69/ea		 £0.00
£381.69/ea £0.00
100 mgQM-0144880-06
100 mgQM-0144880-06
£602.83/ea		 £0.00
£602.83/ea £0.00
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GNF-5837 [CAS 1033769-28-6]

GNF-5837 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.