Graveoline [CAS 485-61-0]

Graveoline (Rutamine) is an orally active alkaloid with various activities such as antifungal, antiparasitic, anti-inflammatory, and antitumor effects. Graveoline can induce tumor cell apoptosis and autophagy through a reactive oxygen species-mediated pathway. Graveoline has an MIC of 500 μg/mL for Candida albicans. Graveoline can be used in the research of various diseases such as tumors and liver injury[1][2][3][4].

[485-61-0]

C17H13NO3

279.3

O=C1C=C(C2=CC=C(OCO3)C3=C2)N(C)C4=C1C=CC=C4

Apoptosis; Autophagy; Fungal; Interleukin Related; JAK; Parasite; Reactive Oxygen Species (ROS) ; STAT

IL-10; IL-4; JAK1; STAT3

10mM

99.88

DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335