Griseofulvin [CAS 126-07-8]

Griseofulvin is an orally active antifungal antibiotic with antitumor activity. Griseofulvin induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also has cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand syndrome[1][2][3][4][5][6].

[126-07-8]

C17H17ClO6

352.77

O=C1[C@]2(C(OC)=CC(C[C@H]2C)=O)OC3=C(Cl)C(OC)=CC(OC)=C13

Antibiotic; Apoptosis; Bcl-2 Family; Caspase; Endogenous Metabolite; Fungal; Microtubule/Tubulin; Wee1

Microbial Metabolite

99.07

DMSO : 33.33 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H317, H351, H360

H317, H351, H360