GRP78-IN-1

GRP78-IN-1 exhibits several interactions with GRP78 residues with binding energy of -8.07 kcal/mol. GRP78-IN-1 shows the potent cytotoxic, anti-proliferative in cancer cells. GRP78-IN-1 exhibits promising apoptosis in breast cancer cells and stalls wound healing properties[1].

C21H23FO3

342.4

[H][C@@]12CC[C@]3(O[C@H]3[C@@]14OC(C(CC5=CC=C(C=C5)F)=C4CC[C@H]2C)=O)C

Apoptosis; HSP

HSP70

10 mM in DMSO

Room temperature