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SKU:QM-0150759-01
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GRP78-IN-3 (Compound 8) is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 μM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 μM) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 μM) [1].
[2707510-30-1]
C17H18N4O2S
342.42
O=C(C1=CC2=C(N1)C=CC=C2)N[C@H](C(NC3=NC=CS3)=O)C(C)C
HSP
HSP70; HSPA5
99.88
DMSO : 5 mg/mL (ultrasonic)
-20°C, 3 years (Powder)
Blue Ice
H302, H315, H319
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GRP78-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.