GS-443902 [CAS 1355149-45-9]

GS-443902 (GS-441524 triphosphate) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir[1][2].

[1355149-45-9]

C12H16N5O13P3

531.2

O=P(OP(O)(O)=O)(O)OP(OC[C@@H](O1)[C@@H](O)[C@@H](O)[C@]1(C#N)C2=CC=C3N2N=CN=C3N)(O)=O

DNA/RNA Synthesis; Drug Metabolite; HCV; RSV; SARS-CoV

99.87

H2O : 100 mg/mL (ultrasonic)

-20°C (Powder, stored under nitrogen)

Blue Ice