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GSK-3685032 [CAS 2170137-61-6]
GSK-3685032 [CAS 2170137-61-6]
SKU:QM-0076395-01
£129.63 GBP
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Product Details
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Description
GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition[1].
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CAS Number
[2170137-61-6]
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Molecular Formula
C22H24N6OS
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Molecular Weight
420.53
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Smiles
N#CC1=C(SC(C2=CC=CC=C2)C(N)=O)N=C(N3CCC(CC3)N)C(C#N)=C1CC
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Target
DNA Methyltransferase
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Purity
99.95
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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GSK-3685032 [CAS 2170137-61-6]
GSK-3685032 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.