GSK-A1 [CAS 1416334-69-4]
GSK-A1 [CAS 1416334-69-4]
SKU:QM-0141431-01
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Product Details
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Description
GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC50 of 8.5-9.8. GSK-A1 inhibits PtdIns (4,5) P2 resynthesis with an IC50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns (4) P with a negligible effect on PtdIns (4,5) P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV) research[1].
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CAS Number
[1416334-69-4]
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Molecular Formula
C29H27FN6O4S
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Molecular Weight
574.63
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Smiles
O=S(C1=CC(C2=CC=C3N=C(N)N(C4=CC=C(N5CCOCC5)C=C4)C3=C2)=CN=C1OC)(NC6=CC=CC=C6F)=O
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Target
HCV; PI4K
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Isoform
PI4K; PI4KIIIα; PI4KIIIβ
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Purity
99.04
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Solubility
DMSO : ≥ 2 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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GSK-A1 [CAS 1416334-69-4]
GSK-A1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.