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GSK223 [CAS 899758-61-3]
GSK223 [CAS 899758-61-3]
SKU:QM-0125551
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Product Details
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Description
GSK223 is a quinazolinone NOD1 pathway inhibitor with potential anti-inflammatory activity. GSK223 can selectively inhibit IL-8 release under iE-DAP stimulation without affecting IL-8 secretion caused by TNF receptor, TLR2 or NOD2 agonists. GSK223 does not directly inhibit RIP2 kinase activity.
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CAS Number
[899758-61-3]
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Molecular Formula
C21H18FN3O3S2
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Molecular Weight
443.51
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Smiles
O=S(C1=CC=C(S1)CC)(NC2=CC(N3C(C)=NC4=C(C3=O)C=CC=C4)=CC=C2F)=O
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Target
NOD-like Receptor (NLR)
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Shipping Conditions
Room temperature
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GSK223 [CAS 899758-61-3]
GSK223 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.