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GSK2945 [CAS 1438071-12-5]
GSK2945 [CAS 1438071-12-5]
SKU:QM-0059353
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Product Details
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Description
GSK2945 is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism[1].
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CAS Number
[1438071-12-5]
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Molecular Formula
C20H18Cl2N2O2S
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Molecular Weight
421.34
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Smiles
O=[N+](C1=CC=C(CN(CC2=CC=C(Cl)C=C2C)CC3=CC=C(Cl)C=C3)S1)[O-]
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Target
Cytochrome P450; REV-ERB
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Solubility
DMSO : 83.33 mg/mL (ultrasonic)
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Shipping Conditions
Room temperature
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GSK2945 [CAS 1438071-12-5]
GSK2945 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.