GSK3179106 [CAS 1627856-64-7]
GSK3179106 [CAS 1627856-64-7]
SKU:QM-0079344-01
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Product Details
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Description
GSK3179106 is an orally active and selective RET kinase inhibitor with IC50s of 0.4 nM, 0.2 nM for human RET and rat RET, respectively. GSK3179106 has the potential for irritable bowel syndrome (IBS) through the attenuation of post-inflammatory and stress-induced visceral hypersensitivity[1].
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CAS Number
[1627856-64-7]
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Molecular Formula
C22H21F4N3O4
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Molecular Weight
467.41
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Smiles
O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)CC2=CC=C(C(C(OCC)=C3)=CNC3=O)C=C2F
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Target
RET
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Purity
99.81
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Solubility
DMSO : ≥ 100 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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GSK3179106 [CAS 1627856-64-7]
GSK3179106 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.