GSK3326595 [CAS 1616392-22-3]
GSK3326595 [CAS 1616392-22-3]
SKU:QM-0081375-01
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Product Details
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Description
GSK3326595 is a protein arginine methyltransferase 5 (PRMT5) inhibitor. GSK3326595 decreases SARS-CoV-2 infection, inhibits cancer cell proliferation and induces pro-inflammatory macrophage polarization and increases hepatic triglyceride levels without affecting atherosclerosis. GSK3326595 can be used for research of relapsed/refractory mantle cell lymphoma[1][2][3][4][5].
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CAS Number
[1616392-22-3]
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Molecular Formula
C24H32N6O3
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Molecular Weight
452.55
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Smiles
O=C(C)N1CCC(NC2=NC=NC(C(NC[C@H](O)CN3CCC(C=CC=C4)=C4C3)=O)=C2)CC1
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Target
Apoptosis; CDK; Histone Methyltransferase; MDM-2/p53; SARS-CoV
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Isoform
CDK4; CDK6; PRMT5
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Purity
99.83
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Solubility
DMSO : 62.5 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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GSK3326595 [CAS 1616392-22-3]
GSK3326595 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.