GSK4418959 (enantiomer) [CAS 3064599-37-4]
GSK4418959 (enantiomer) [CAS 3064599-37-4]
SKU:QM-0008828-01
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Product Details
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Description
GSK4418959 enantiomer is an enantiomer of GSK4418959. GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner. GSK4418959 can be used for the study of microsatellite instability-high (MSI-H) cancer[1].
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CAS Number
[3064599-37-4]
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Molecular Formula
C31H30F4N4O5S
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Molecular Weight
646.65
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Smiles
O=S(C1=CC=C(N(C(C)=N2)C)C2=C1)(N(C3=CC=C([C@@H]4CCC[C@@H]([C@H]4C(O)=O)C(NC5=C(F)C=C(C(F)(F)F)C=C5)=O)C=C3)C)=O
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Target
DNA/RNA Synthesis
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Concentration
10mM
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Purity
95
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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GSK4418959 (enantiomer) [CAS 3064599-37-4]
GSK4418959 (enantiomer) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.