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GSK583 [CAS 1346547-00-9]
GSK583 [CAS 1346547-00-9]
SKU:QM-0079222-01
£119.50 GBP
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Product Details
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Description
GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.
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CAS Number
[1346547-00-9]
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Molecular Formula
C20H19FN4O2S
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Molecular Weight
398.45
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Smiles
FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
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Target
RIP kinase
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Purity
99.93
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Solubility
DMSO : ≥ 100 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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GSK583 [CAS 1346547-00-9]
GSK583 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.