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GSPT1 degrader-11
GSPT1 degrader-11
SKU:QM-0014749
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Product Details
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Description
GSPT1 degrader-11 is a CRBN-dependent G1 to S phase transition 1 (GSPT1) molecular glue degrader (DC50 = 67.7 nM, Dmax = 97%) . GSPT1 degrader-11 can inhibit MDA-MB-231 CRBN-WT cells proliferation (IC50 = 2.07 μM) . GSPT1 degrader-11 can be used for the research of cancer[1].
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Molecular Formula
C41H45N11O5
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Molecular Weight
771.87
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Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(N4CC(N5CCC(C(N6CCN(C7=CC=C(NC8=NC=C9N=C(C%10CC%10)N(C)C9=N8)C=C7)CC6)=O)CC5)C4)=C3)=O
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Target
Molecular Glues
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Shipping Conditions
Room temperature
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GSPT1 degrader-11
GSPT1 degrader-11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.