GSTO1-IN-3 [CAS 158890-32-5]

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SKU:QM-0052529

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Product Details

Description
GSTO1-IN-3 is a potent GSTO1-1 inhibitor with an IC50 of 0.11 μM, and shows selectivity over GSTO2-2, GSTA1-1 and GSTP1-1 (IC50 > 100 μM). GSTO1-IN-3 enhances the cytotoxicity of Cisplatin against human breast cancer cells. GSTO1-IN-3 inhibits IL-1β release in mouse bone marrow-derived macrophage (BMDM) cells. GSTO1-IN-3 attenuates inflammation in mice. GSTO1-IN-3 can be used for breast cancer and inflammation research[1].
CAS Number
[158890-32-5]
Molecular Formula
C14H18ClNO
Molecular Weight
251.75
Smiles
O=C(N1CCC(CC1)CC2=CC=CC=C2)CCl
Target
Glutathione S-transferase; Interleukin Related
Shipping Conditions
Room temperature
Hazard Statement
H302-H315-H318-H335
Precautions
P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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GSTO1-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.