GSTO1-IN-4 [CAS 158890-33-6]

GSTO1-IN-4 is a selective, potent GSTO1-1 inhibitor (IC50 = 0.04 μM; KI = 0.16 μM). GSTO1-IN-4 shows low inhibition to GSTO2-2, GSTA1-1 and GSTP1-1. GSTO1-IN-4 shows a capacity to attenuate inflammation in mice and to significantly enhance the cytotoxicity of Cisplatin. GSTO1-IN-4 can be used for the study of inflammation and breast cancer[1].

[158890-33-6]

C16H22ClNO

279.8

O=C(N1CCC(CC1)CCCC2=CC=CC=C2)CCl

Glutathione S-transferase

Room temperature