GW-3333 [CAS 212609-68-2]

GW-3333 is a potent and orally active TNF-alpha-converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitor. GW-3333 inhibits tumor necrosis factor-alpha (TNF-alpha) production. GW-3333 can be used in research of arthritis[1][2].

[212609-68-2]

C22H36N4O4

420.55

CC[C@@H]([C@H](NC([C@@H]([C@@H](N(O)C=O)C(C)C)CC(C)C)=O)C(NC1=CC=CC=N1)=O)C

MMP; TNF Receptor

10 mM in DMSO

Room temperature