GW2974 [CAS 202272-68-2]

GW2974 is a potent dual inhibitor of EGFR and HER2 with IC50 value of 0.007 μM and 0.016 μM, respectively. GW2974 demonstrates in vitro inhibition of the EGFR and HER2 and inhibits the growth of tumor cell. GW2974 can be used for glioblastoma multiforme (GBM) disease research[1][2].

[202272-68-2]

C23H21N7

395.46

CN(C)C1=CC2=C(NC3=CC4=C(N(CC5=CC=CC=C5)N=C4)C=C3)N=CN=C2C=N1

EGFR

EGFR/ErbB1/HER1; ErbB2/HER2

99.54

DMSO : 20 mg/mL (ultrasonic; warming)

4°C (Powder, sealed storage, away from moisture)

Room Temperature