Halicin [CAS 40045-50-9]

Halicin (SU3327) is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM. Halicin also inhibits protein-protein interactions between JNK and JNK Interacting Protein (JIP) with an IC50 of 239 nM. Halicin shows less active against p38α and Akt kinase[1][2].

[40045-50-9]

C5H3N5O2S3

261.3

NC1=NN=C(S1)SC2=NC=C([N+]([O-])=O)S2

JNK

10mM

98.92

DMSO : 62.5 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315, H319

H315, H319