HAT-IN-9

HAT-IN-9 (Compound 3F) is a selective proliferation inhibitor targeting Trypanosoma brucei. HAT-IN-9 inhibits the proliferation and division of Trypanosoma brucei. HAT-IN-9 is promising for research of African trypanosomiasis (HAT, i.e., sleeping sickness) [1].

C25H20F3N5O3

495.45

FC(F)(F)C1=C(C=CC(NC2=NC=NC3=CC=C(C=C23)C4=CC=CC(N5CCOCC5)=C4)=C1)[N+]([O-])=O

Parasite

Room temperature