HCAI/II-IN-2 [CAS 2480283-75-6]

HCAI/II-IN-2 (compound 2b) is a potent dual hCA I/II inhibitor with Ki values of 40.97, 15.15 and 61.88 nM for hCA I, hCA II and hCA IX. hCAI/II-IN-2 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity[1].

[2480283-75-6]

C12H12N4O5S2

356.38

O=C(C1=NN=C(NC(C2=CC=C(S(=O)(N)=O)C=C2)=O)S1)OCC

Carbonic Anhydrase

CA II; CA I

10 mM in DMSO

Room temperature