HCAIX/XII-IN-1 [CAS 3033040-76-2]

HCAIX/XII-IN-1 is a potent CAIX/XII inhibitor with the KI values of 0.48 μM and 0.83 μM for CAIX and CAXII, respectively. hCAIX/XII-IN-1 shows antiproliferative activity in vitro. hCAIX/XII-IN-1 induces apoptosis in MCF-7 cells[1].

[3033040-76-2]

C19H11NO5S2

397.42

O=C(C1=CC2=C(OC1=O)C=CC=C2)CN3C(S/C(C3=O)=C\C4=CC=CS4)=O

Apoptosis; Carbonic Anhydrase

CA IX

10 mM in DMSO

Room temperature